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What are NAD+ injections used for?

By Dr. Paul C. Holmwood, MD. Published . 1 min read.

NAD+ injections deliver nicotinamide adenine dinucleotide, a coenzyme involved in cellular energy metabolism and DNA repair, as a prescription medication injected under the skin. Providers prescribe it off-label for adults interested in energy, mental focus and healthy-aging support, with the understanding that NAD+ is not FDA-approved and the human evidence is still developing.

What this means for you

NAD+ levels decline with age, which is the rationale behind supplementing it, but the step from that observation to a proven benefit in people has not been completed in large trials. An honest provider frames NAD+ as a reasonable option for some patients rather than a treatment for a diagnosis. Injections are distinct from IV infusions, which deliver larger amounts over hours at a clinic, and from oral precursor supplements such as NMN and NR.

How it works at Biotech Lifestyle

A licensed provider reviews your history and goals, explains the evidence and decides whether NAD+ is appropriate for you. When prescribed, it is compounded by a licensed U.S. pharmacy with a labeled concentration and instructions for home use.

Treatment pages: NAD+, longevity medicine. Related reading: NAD+ Injection Benefits. All of our patient FAQs are collected on one page.

Frequently asked questions

What are NAD+ injections used for?

NAD+ injections deliver nicotinamide adenine dinucleotide, a coenzyme involved in cellular energy metabolism and DNA repair, as a prescription medication injected under the skin. Providers prescribe it off-label for adults interested in energy, mental focus and healthy-aging support, with the understanding that NAD+ is not FDA-approved and the human evidence is still developing.

Are NAD+ injections the same as an NAD+ IV?

No. IV infusions deliver larger amounts over hours at a clinic; prescribed injections are smaller amounts for home use. Reports about one do not describe the other.

What side effects are reported with NAD+ injections?

Nausea, flushing and injection-site discomfort are the most commonly reported. Report anything persistent to your provider rather than adjusting on your own.

What to do next

A licensed provider reviews every assessment.

There is no charge to start.

Start a free online assessment with a licensed provider

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  • Is NAD+ the same as NMN? No. NAD+, nicotinamide adenine dinucleotide, is the coenzyme itself. NMN, nicotinamide mononucleotide, and NR, nicotinamide riboside, are precursors the body can convert into NAD+. Injectable NAD+ delivers the molecule directly by prescription, while NMN and NR are oral supplements.
  • Is NAD+ FDA approved? No. NAD+ is not an FDA-approved drug for any use. Injectable NAD+ is prepared by compounding pharmacies under a prescription, and oral forms such as NMN and NR are regulated as dietary supplements, which the FDA does not approve before they are sold.
  • Do you need a prescription for NAD+ injections? Yes. Injectable NAD+ is a compounded prescription medication: a licensed provider must evaluate you and write a prescription, and a licensed pharmacy prepares it. Oral NAD+ precursors such as NMN and NR are sold as dietary supplements without a prescription, but they are not the same product.

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This article is for information only and is not medical advice. Compounded medications are prepared by licensed pharmacies for individual patients and are not FDA-approved. Prescriptions are issued only after evaluation by a licensed provider. Individual results vary.